GLP-1 (Glucagon-Like Peptide-1) An incretin hormone produced in the gut that reduces appetite through hypothalamic signaling, slows gastric emptying, and stimulates insulin secretion
Common mistake: Trying to eat your normal diet
Metformin frequently causes gastrointestinal side effects including diarrhea, nausea, abdominal discomfort, and metallic taste, affecting approximately 20-30% of patients, particularly during initiation
In the SURMOUNT-1 study, adults without diabetes receiving tirzepatide 15 mg experienced an average weight reduction of 20.9% after 72 weeks
Of course regular exercise, maintaining a healthy weight and avoiding smoking or excess alcohol consumption reduces your risk, Dr
Blood sugar controlNot surprisingly, blood sugar control also features strongly in the evidence base