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Post PSM, participants in the GLP-1 RA group had a higher BMI and HbA 1c compared with the SGLT2i cohort

Finally, the review addresses the broader implications of these findings for geroscience and outlines future directions for investigating the potential of GLP-1 RAs in healthspan extension, while also acknowledging the limitations and potential biases inherent in this analytical review

doi: 10.3389/fnagi.2026.1851072 Received 09 April 2026 Revised 18 May 2026 Accepted 20 May 2026 Published 05 June 2026 Volume 18 - 2026 Edited by Scott E

Its essential to follow professional guidance when determining the right regimen

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