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Similarly, GLP-1R activation on the axons from dispersed SPNs in the ICN, and possibly CAA, may account for other, rarer side effects of GLP-1R agonists

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Similarly, semaglutide increased natriuresis in Glp1r VSM+/+ mice, as shown by higher urine sodium and chloride concentrations (normalized to urine creatinine levels)actions attenuated, but not completely eliminated, in Glp1r VSM/ mice (Figure 4, B and C)

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Healthcare providers can make Vitamin B12 therapy more effective by watching how patients react to the treatment